This comprehensive guide breaks down the sharpest MLB wagers for Friday, August 8, 2025. From best moneyline and run-line plays to first-5 innings, game totals, NRFI bets and standout pitcher/player props, we cover every angle. Plus, discover our favorite home run prop parlay and multi-leg parlays to maximize your edge on tonight’s slate.

BEST MONEY LINE BETS

Milwaukee Brewers ML (-140) vs Mets ✅— Brandon Woodruff has looked fantastic since returning, while the Mets’ first-inning (and recent) production is bottom-tier; with Kodai Senga still a bit volatile post-break, Milwaukee’s home edge and starting pitching tilt the moneyline toward the Crew

Cincinnati Reds ML (-120) at Pirates ❌— Market support has lined up on Cincinnati with the total ticking down, reflecting respect for the Reds’ edge in this matchup; the consensus also leans Under, which often correlates with tighter, favored-road-win scripts

Miami Marlins ML (-125) ✅at Braves

Los Angeles Angels ML (+250) at Detroit Tigers)  ❌Tigers starting pitcher Tarik Skubal is great, but we can’t ignore such a attractive price on underdog. The Angles are not bad at all.

Chicago White Sox ML (+125) ❌ vs Cleveland Guardians

Boston Red Sox ML (+150) ✅ at San Diego Padres

BEST RUN LINE BETS

Brewers -1.5 Run Line (+150)  ❌vs Mets — Woodruff’s strikeout form and the Mets’ weak first-inning and recent offensive splits support a multi-run Milwaukee result if their bats give modest support against Senga

Cincinnati Reds -1.5 Run Line (+140) ❌

Arizona Diamondbacks -1.5 Run Line (-120) ✅

Los Angeles Angels at Detroit Tigers UNDER 4 (-110) 1st Five Innings ❌

↕️ BEST GAME TOTAL BETS

Reds–Pirates Under 7.5 (-110)   ✅— Market moved from 8 down to 7.5 with consensus on the Under, reflecting sharper sentiment on run suppression at PNC; align with the move.

Rays–Mariners Under 7 (+100)  ✅— Luis Castillo’s elite NRFI/early-game profile and Drew Rasmussen’s strong season underpin a full-game Under lean in a run-suppressing park; NRFI modeling supports low-scoring opens cascading through nine.

Blue Jays–Dodgers Over 9 (+100)  ❌— Toronto’s recent Over trend plus a matchup that sets up power contact for the Jays (see Vlad Jr. TB edge vs LHP) argues for runs exceeding the posted total; keep an eye on late market drift.

Rockies–D-backs Over 9 (-110) ❌ — With Austin Gomber’s struggles and right-handed thump like Ketel Marte well-positioned, run creation conditions favor an Over in the desert.

Athletics at Baltimore Orioles OVER 9.5  ❌(-115)

Kansas City Royals at Minnesota Twins OVER 8 (-120) ✅

BEST TEAM TOTAL BETS

Arizona Diamondbacks Team Total Over 5.5 (+110)  ✅— Ketel Marte and Arizona’s RH core project well vs LHP Austin Gomber; contact quality and matchup indicators support a D-backs scoring lean.

Angels at Tigers — RFI  NO @ -125 ✅. Skubal owns a 19–3 NRFI record with top-10 xFIP/WHIP and K-rate in first innings; the Angels’ first-inning K% and underpowered splits vs LHP bolster this edge. Hendricks has also held his own early, while Detroit’s first-inning offense has been quiet lately

Royals at Twins — NRFI (-125) ❌. Seth Lugo (18–3 NRFI) vs Joe Ryan (17–4 NRFI) with both lineups posting bottom-tier first-inning production lately; strong pitcher/park combination to stay quiet through six outs.

Nick Pivetta (SDP) Under 1.5 Earned Runs (+125) ❌ — Market-available plus-money angle highlighted by Covers; matchup context in Petco and his 2025 form support a low ER outcome in this spot [Covers](https://www.covers.com/mlb/player-props-best-bets-friday-8-8-2025).

Vladimir Guerrero Jr. (TOR) Over 1.5 Total Bases (+105) vs Dodgers ✅ — Elite splits vs LHP fastball/slider (majority of Kershaw’s mix) put Vlad Jr. in a prime contact/power spot tonight [DraftKings Network](https://dknetwork.draftkings.com/2025/08/08/mlb-picks-for-august-8-2025-best-player-props-and-team-bets/).

Manny Machado (SDP) Over 1.5 Total Bases (+115)  ❌— Machado’s batted-ball authority and Petco matchup create multiple paths to two total bases; plus-money was noted in market snapshots (+120).

Ketel Marte (ARZ) OVER 2.5 Hits + Runs + RBI (-115) ✅ — Favorable handedness and pitch-type matchup vs LHP Gomber, with leadoff volume adding extra routes to cash the combo.

Michael Conforto (LAD) OVER 1.5 Hits + Runs + RBI (+125) ❌ – he’s facing Scherzer his favorite pitcher, who seriously improved his stats.

Freddie Freeman (LAD) OVER 1.5 Hits + Runs + RBI (-135) ❌

Fernando Tatis Jr. (SDP) OVER 2.5 Hits + Runs + RBI (+125) ❌

Corbin Carroll (ARZ) OVER 2.5 Hits + Runs + RBI (+110) ✅

Lourdes Gurriel Jr. (ARZ) OVER 2.5 Hits + Runs + RBI (+115) ❌

Mickey Moniak (COL) OVER 1.5 Hits + Runs + RBI (-105) ❌

Tyler Stephenson (CIN) OVER 1.5 Hits + Runs + RBI (+115) ✅

Fernando Tatis Jr. (SDP) Home Run @ +390  ❌range cited across outlets; elite power/speed skillset in a matchup flagged as favorable for San Diego hitters.

Kerry Carpenter  (Detroit Tigers) Home Run @  ❌+360 noted; left-handed thump in a game environment that expects run creation for Detroit.

Tyler Soderstrom (Athletics)  Home Run @ +375 ❌ longshot with role/power aligned for volatility; included among best HR targets today.

Shea Langeliers (Athletics)  Home Run @ +350  ❌cited with underlying power skills and matchup support.

Michael Conforto (LAD) Home Run @ +345 ❌

Ketel Marte (ARZ) Home Run @ +250 ❌

🏆BEST HOME RUN PROPS ROUND ROBIN PARLAY 🏆+$7,714

Michael Conforto (LAD) Home Run @ +345
Kerry Carpenter  (Detroit Tigers) Home Run @ +360
Tyler Soderstrom (Athletics)  Home Run @ +375
Ketel Marte (ARZ) Home Run @ +250


2-3-4 ROUND ROBIN 11 bests 0.1 UNIT Each leg. Total 1.1 Units Play Estimated Combined Odds: $110 ❌ bet potential win $7,714

2️⃣ 2-LEG PARLAY OF THE DAY (+214)

Cincinnati Reds ML (-120) ❌ + Milwaukee Brewers ML (-140) 

1 UNIT Play Estimated Combined Odds: $100  ❌bet potential win $214

2️⃣ BEST 2-LEG PARLAY OF THE DAY (+244)

Reds–Pirates Under 7.5 (-110) ✅ + Miami Marlins ML (-125)  ✅

1 UNIT Play Estimated Combined Odds: $100 bet potential win $244 ✅ ✅

3️⃣ BEST 3-LEG PARLAY OF THE DAY (+654)

Arizona Diamondbacks -1.5 Run Line (-120) ✅ + Brewers ML (-140) ✅ +  Cincinnati Reds -1.5 Run Line (+140) ❌

1 UNIT Play Estimated Combined Odds: $100 bet  ❌potential win $654

4️⃣ BEST 4-LEG PARLAY OF THE DAY (+1150)

Reds–Pirates Under 7.5  ✅+ Blue Jays–Dodgers Over 9 (+100) ❌  + Brewers ML  ✅+ Rays–Mariners Under 7  ✅— Leverages an aligned market move and three strong starting pitching-driven edges to create diversified exposure across sides and totals 

1 UNIT Play Estimated Combined Odds: $100 ❌ bet potential win $1,150

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