The top MLB wagering recommendations for Wednesday, August 13, 2025, including money line, run line, first-five innings, totals, NRFI, pitcher and player props, and parlay plays. Each pick is supported by confirmed probable pitchers, current odds, and insights from leading sports-betting analysts. Detailed sources accompany every selection to help bettors make informed decisions.

BEST MONEY LINE BETS

San Francisco Giants ML (+135) vs San Diego Padres

Cincinnati Reds ML (+110) vs Phillies

Boston Red Sox ML (+141) at Houston Astros

Toronto Blue Jays ML (-126) vs Cubs. Gausman vs rookie Horton; Jays favored at home

Colorado Rockies ML (+197) at St. Louis Cardinals – big underdog winning two in a row, away at big club, doesn’t sound appealing, but we like the price on it.

BEST RUN LINE BETS

Milwaukee Brewers -1.5 (-125) vs Pittsburgh Pirates

New York Yankees -1.5 (+140) vs Twins 

New York Mets -1.5 (+105) vs Braves. Peterson advantage and market RL plus-money

Toronto Blue Jays -1.5 (+160) vs Cubs. Home edge with Gausman; RL price attractive.

Tampa Bay Rays -1.5 (+125) at Athletics. Rasmussen vs Ginn; RL pricing favorable

  • Los Angeles Dodgers at Los Angeles Angels F5 OVER 5 (-110) 
  • Miami Marlins 1st 5 ML (-105) at Guardians
  • Toronto Blue Jays 1st 5 ML (-135) vs Cubs. Jays have cashed F5 ML in 11 of last 16 home games; matchup: Gausman vs Horton

↕️ BEST GAME TOTAL BETS

Atlanta Braves at New York Mets UNDER 9 (-115)

Miami Marlins at Cleveland Guardians OVER 7.5 (-120)

Tampa Bay Rays at Athletics OVER 9.5 (+100) 

Los Angeles Dodgers at Los Angeles Angels OVER 9.5 (-105) 

Seattle Mariners at Baltimore Orioles UNDER 8.5 (-110)

BEST TEAM TOTAL BETS

Toronto Blue Jays Team Total OVER 4.5 (+100) vs Cubs. Jays have hit team total over in 40 of their last 65; Horton on road

Los Angeles Dodgers Team Total OVER 5.5 (-110)  

Tampa Bay Rays Team Total OVER 4.5 (-120) 

San Diego Padres at San Francisco Giants OVER 0.5 Run in 1st Inning (+105) 

Tampa Bay Rays at Athletics OVER 0.5 Run in 1st Inning (-115) 

Merrill Kelly [Rangers] UNDER 5.5 Ks (-105)

Joe Ryan [Twins] UNDER 6.5 Ks (+100). Market shade to under vs disciplined Yankees lineup. 

Kevin Gausman [Blue Jays] UNDER 5.5 Ks (-118). Market leans under 5.5; Cubs’ contact profile

Zac Gallen [Diamondbacks] OVER 4.5 Ks (-160)

Brandon Lowe [Rays] OVER 1.5 Hits + Runs + RBI (-140) . Featured as a top play; strong matchup vs J.T. Ginn.

Vladimir Guerrero Jr. [Blue Jays] OVER 1.5 Hits + Runs + RBI (-140)

Bo Bichette [Blue Jays] OVER 1.5 Hits + Runs + RBI (-145)

Ryan Jeffers [Twins] OVER 1.5 Hits + Runs + RBI (-105)

Jazz Chisholm Jr. [Yankees] OVER 1.5 Hits + Runs + RBI (+110)

Christian Walker (Astros) OVER 1.5 Hits + Runs + RBI (-115)

Matt Olson (Braves) OVER 1.5 Hits + Runs + RBI (+100)

Matt Olson (Braves) OVER 1.5 Hits (+250)

William Contreras (Brewers) OVER 1.5 Hits + Runs + RBI (-145)

William Contreras (Brewers) OVER 1.5 Hits (+170) Multiple hits in his last 3 games

Matt Olson (Braves) to hit a Home Run (+500) 

Christian Walker (Astros to hit a Home Run (+450)

William Contreras (Brewers) to hit a Home Run (+400) 

Randy Arozarena (Seattle Mariners) to hit a Home Run (+475) 

🏆BEST HOME RUN PROPS ROUND ROBIN PARLAY 🏆+$18,195

Matt Olson HR (+500) + Christian Walker HR +450 + William Contreras (Brewers) HR +400 + Randy Arozarena (Seattle Mariners) HR +475

2-3-4 ROUND ROBIN 11 bests 0.1 UNIT Each leg. Total 1.1 Units Play Estimated Combined Odds: $110 bet potential win $18,195

2️⃣ 2-LEG PARLAY OF THE DAY (+250)

Toronto Blue Jays ML (-126)  + Miami Marlins 1st 5 ML (-105)

1 UNIT Play Estimated Combined Odds: $100  bet potential win $250 

2️⃣ BEST 2-LEG PARLAY OF THE DAY (+305)

Milwaukee Brewers -1.5 (-125) +Tampa Bay Rays -1.5 (+125)

1 UNIT Play Estimated Combined Odds: $100  bet potential win $305

3️⃣ BEST 3-LEG PARLAY OF THE DAY (+634)

New York Mets -1.5 (+105) +Los Angeles Dodgers at Los Angeles Angels OVER 9.5 (-105)   + Tampa Bay Rays Team Total OVER 4.5 (-120) 

1 UNIT Play Estimated Combined Odds: $100  bet potential win $634

4️⃣ BEST 4-LEG PARLAY OF THE DAY (+1257)

Tampa Bay Rays -1.5 (+125)  +
Christian Walker (Astros) OVER 1.5 Hits + Runs + RBI (-115) +
Los Angeles Dodgers Team Total OVER 5.5 (-110)   +
William Contreras (Brewers) OVER 1.5 Hits + Runs + RBI (-145)

1 UNIT Play Estimated Combined Odds: $100  bet potential win $1,257

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