This comprehensive preview highlights the top MLB betting opportunities for Friday, July 11, 2025, including money line and run line picks, game and team totals, NRFI props, pitcher and player prop bets, home run selections, and value parlays—backed by detailed matchup analysis and weather insights.
BEST MONEY LINE BETS
Boston Red Sox ML (-107) vs. Tampa Bay Rays The Red Sox have been one of the hottest teams in baseball and are favored at home. With strong offensive momentum, they should cover the run line against Tampa Bay.
St. Louis Cardinals (-120) vs. Atlanta Braves The Cardinals are getting slight underdog value at home against the Braves. This presents solid betting value in what should be a competitive National League matchup.
BEST RUN LINE BETS
Detroit Tigers -1.5 Run Line (-110) vs. Seattle Mariners Tarik Skubal (10-2, 2.02 ERA) is having a Cy Young-caliber season and gives the Tigers a significant pitching advantage. The Tigers’ offense has been clicking at home, making the run line attractive at plus odds.
Toronto Blue Jays -1.5 Run Line (-110) at Athletics
Cincinnati Reds -1.5 Run Line (-120) vs. Colorado Rockies
San Francisco Giants First 5 Innings -0.5 (+100)
↕️ BEST GAME TOTAL BETS
Toronto Blue Jays at Oakland Athletics – Over 10.5 Runs (-120) The Blue Jays have the highest team total of the day at 5.5 runs, and the Athletics’ pitching has been inconsistent. Strong winds are expected to blow out at the Coliseum, favoring offensive production.
Pittsburgh Pirates at Minnesota Twins UNDER 7 (-125)
Texas Rangers vs Houston Astros OVER 8 (-125)
BEST TEAM TOTAL BETS
Toronto Blue Jays TEAM TOTAL Over 5.5 Runs (-125) The Blue Jays have the highest team total of the day and are facing Oakland’s inconsistent pitching staff. Toronto’s offense has been productive, making this the strongest team total play.
Cincinnati Reds TEAM TOTAL Over 5.5 Runs (-105) The Reds are facing Colorado’s weak pitching at altitude, creating an excellent environment for offensive production. This represents solid value at near even odds.
BEST NRFI (No Run in First Inning)
Texas Rangers vs. Houston Astros NRFI (-120) Jack Leiter faces Lance McCullers Jr. in a matchup where both pitchers have shown first-inning effectiveness. The equal odds make this a strong NRFI selection.
Los Angeles Dodgers vs. San Francisco Giants NRFI (-140) Despite the higher juice, Logan Webb (2.62 ERA) is one of the most reliable first-inning pitchers in baseball. Dustin May has also shown improvement, supporting the NRFI despite the higher cost.
BEST PITCHER PROPS
Chris Flexen (Chicago Cubs) Under 2.5 Strikeouts (+110) Flexen has only 17 strikeouts in 32⅔ innings pitched, making the under on strikeouts an excellent value play at even odds.
Ryne Nelson (Arizona Diamondbacks) Total Earned Runs Allowed UNDER 2.5 (-115) Nelson has been solid for Arizona and gets a favorable matchup against the Angels. Odds provide excellent value.
BEST PLAYER PROPS
Elly De La Cruz (Cincinnati Reds) Over 1.5 Total Bases (-125) De La Cruz has been one of the most explosive players in baseball and should find success against Colorado’s pitching.
Vladimir Guerrero Jr. (Toronto Blue Jays) Over 1.5 Total Bases (-110) Guerrero Jr. has been heating up and faces Oakland’s struggling pitching staff, making this an excellent value play.
Tyler Soderstrom (Athletics) Over 1.5 Hits+Runs+RBI (-115) The young Athletics prospect has been impressive and should contribute multiple ways against Toronto’s pitching.
BEST HOME RUN PROPS
Jazz Chisholm Jr. (NY Yankees) Home Run (+425) The Yankees star is participating in the upcoming Home Run Derby and has been locked in. The +400 odds provide excellent value for a power hitter in a favorable matchup.
Seiya Suzuki (Chicago Cubs) Home Run (+400) The Cubs outfielder has been consistent with his power stroke and gets a favorable matchup against left-handed pitching.
Corey Seager (Texas Rangers) Home Run (+425) The Rangers slugger has been one of the most reliable home run hitters in baseball and benefits from strong wind conditions in Houston.
Vladimir Guerrero Jr. (Toronto Blue Jays) Home Run (+400) perfect ballpark for Vladimir Jr. to hit some bombs.
Kyle Schwarber (Phillies) Home Run (+250)
2️⃣ BEST 2-LEG PARLAY OF THE DAY
- Detroit Tigers -1.5 Run Line (-110)
- Toronto Blue Jays at Oakland Athletics – Over 10.5 Runs (-120)
1 UNIT Play Estimated Combined Odds: $100 bet potential win $250
3️⃣ BEST 3-LEG PARLAY OF THE DAY
Value Parlay (+621)
- Boston Red Sox ML (-107)
- San Francisco Giants First 5 Innings -0.5 (-105)
- Detroit Tigers -1.5 (-110)
1 UNIT Play Estimated Combined Odds: $100 bet potential win $621
This parlay combines three strong individual plays with excellent value. The Red Sox are hot, the Giants have Logan Webb on the mound, and the Tigers have Tarik Skubal dealing.
🏆ROUND ROBIN HOME RUN PARLAY🏆
4️⃣ 4-3-2 ROUND ROBIN HOME RUN PROPS PARLAY
4-3-2 ROUND ROBIN Home Run Parlay (+12,167)
- Jazz Chisholm Jr. (NY Yankees) Home Run (+425)
- Seiya Suzuki (Chicago Cubs) Home Run (+400)
- Corey Seager (Texas Rangers) Home Run (+350)
- Vladimir Guerrero Jr. (Toronto Blue Jays) Home Run (+400)
2-3-4 ROUND ROBIN 11 bests 0.1 UNIT Each leg. Total 1.1 Units Play Estimated Combined Odds: $110 bet potential win $12,167
This massive payout parlay combines four of the day’s best home run candidates. While the odds are long, each player has legitimate home run upside in their respective matchups.
Weather Considerations: Most games have favorable weather conditions with no rain expected. The Mets-Royals and Rangers-Astros games feature strong outward winds that could boost offensive production, making overs and home run props more attractive.
These recommendations are based on comprehensive analysis of pitching matchups, team statistics, weather conditions, and current betting market inefficiencies. Always remember to bet responsibly and within your means.
